Who Makes Jemperli (dostarlimab-gxly): Manufacturer Overview

Jemperli is manufactured by GlaxoSmithKline (GSK), a global biopharma company. AnaptysBio discovered Jemperli (dostarlimab-gxly) and licensed it to TESARO, Inc. under a collaboration and exclusive license agreement signed in March 2014.

GSK acquired TESARO on December 3, 2018, and became responsible for the ongoing research, development, commercialization, and manufacturing of Jemperli.

Jemperli Manufacturer Overview

Trade Name	Jemperli
Manufacturer	GlaxoSmithKline (GSK)
Active Ingredient	Dostarlimab-gxly
Formula	C₆₄₂₀H₉₈₃₂N₁₆₉₀O₂₀₁₄S₄₄
FDA-Approval Date	April 22, 2021
FDA-Approved Uses	Advanced or recurrent endometrial cancer DNA mismatch repair deficient (dMMR) Microsatellite instability-high (MSI-H)
Website	https://jemperli.com

What Does Jemperli Treat?

Jemperli is an immunotherapy medication approved by the FDA for the treatment of certain types of endometrial cancer in adults. Here’s a breakdown of its specific indications:

Advanced or recurrent endometrial cancer: This refers to cancer that has either spread to other parts of the body or come back after previous treatment.
DNA mismatch repair deficient (dMMR) and microsatellite instability-high (MSI-H) mutations: These are specific genetic changes found in some cancer cells that make them more vulnerable to the immune system’s attacks. Jemperli is only effective for endometrial cancer with these specific genetic markers, which can be identified through specific tests.

It’s important to note that Jemperli is not a cure for cancer but can be a valuable treatment option for specific types and stages of endometrial cancer, particularly those with dMMR/MSI-H mutations. Jemperli is a prescription medication and should only be taken under the supervision of a healthcare professional. They can determine if Jemperli is the right treatment for your specific condition and address any potential risks or side effects.

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